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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
31.21
Human Site:
S181
Identified Species:
49.05
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
S181
N
C
P
P
H
I
E
S
F
S
D
V
E
M
G
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
N179
N
C
P
P
H
I
E
N
F
G
D
I
D
M
G
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
S431
N
C
P
P
H
I
E
S
F
S
D
V
E
M
G
Dog
Lupus familis
XP_861268
662
73195
S181
N
C
P
P
H
I
E
S
F
S
D
V
E
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
S181
N
C
P
P
H
I
E
S
F
S
D
V
E
M
G
Rat
Rattus norvegicus
NP_001102328
659
72976
S179
N
C
P
P
H
I
E
S
F
S
D
V
E
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
E175
F
S
D
V
E
M
G
E
I
I
M
G
N
I
E
Chicken
Gallus gallus
NP_001025971
651
72031
M179
E
S
F
S
D
V
D
M
G
E
I
I
M
G
N
Frog
Xenopus laevis
P24346
697
77284
S222
N
C
P
P
H
I
E
S
F
H
D
V
T
M
G
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
R209
N
G
P
Q
P
I
D
R
F
H
D
L
E
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
S296
N
V
P
P
N
I
T
S
F
D
D
V
Q
L
T
Honey Bee
Apis mellifera
XP_391829
701
78642
S224
N
I
P
P
H
I
T
S
F
D
E
V
K
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
N175
K
P
T
P
V
Q
R
N
A
I
P
I
L
A
A
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
K170
E
L
L
M
E
N
I
K
L
A
S
F
T
K
P
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
T195
N
V
P
E
P
V
L
T
F
S
N
P
P
L
D
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
0
0
86.6
53.3
N.A.
53.3
53.3
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
13.3
20
86.6
66.6
N.A.
73.3
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
7
0
0
0
7
7
% A
% Cys:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
14
0
0
14
60
0
7
0
7
% D
% Glu:
14
0
0
7
14
0
47
7
0
7
7
0
40
0
7
% E
% Phe:
7
0
7
0
0
0
0
0
74
0
0
7
0
0
0
% F
% Gly:
0
7
0
0
0
0
7
0
7
7
0
7
0
7
54
% G
% His:
0
0
0
0
54
0
0
0
0
14
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
67
7
0
7
14
7
20
0
7
0
% I
% Lys:
7
0
0
0
0
0
0
7
0
0
0
0
7
7
0
% K
% Leu:
0
7
7
0
0
0
7
0
7
0
0
7
7
20
0
% L
% Met:
0
0
0
7
0
7
0
7
0
0
7
0
7
54
0
% M
% Asn:
74
0
0
0
7
7
0
14
0
0
7
0
7
0
7
% N
% Pro:
0
7
74
67
14
0
0
0
0
0
7
7
7
0
7
% P
% Gln:
0
0
0
7
0
7
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% R
% Ser:
0
14
0
7
0
0
0
54
0
40
7
0
0
0
0
% S
% Thr:
0
0
7
0
0
0
14
7
0
0
0
0
14
0
14
% T
% Val:
0
14
0
7
7
14
0
0
0
0
0
54
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _